LDN-27219 drug mechanism of action Things To Know Before You Buy
One particular specifically attention-grabbing compound is LDN-27219. Though most tTG inhibitors are meant to bind on the protein crosslinking active web page, LDN-27219 in its place binds on the nucleotide binding pocket in the enzyme whilst it is actually in its closed-condition conformation, and stabilizes that conformation to prevent crosslinki